home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9409a.zip
/
M9490059.TXT
< prev
next >
Wrap
Text File
|
1994-09-03
|
2KB
|
32 lines
Document 0059
DOCN M9490059
TI Significance of oral examination in chronic graft-versus-host disease.
DT 9411
AU Hiroki A; Nakamura S; Shinohara M; Oka M; Second Department of Oral and
Maxillofacial Surgery, Kyushu; University, Fukuoka, Japan.
SO J Oral Pathol Med. 1994 May;23(5):209-15. Unique Identifier : AIDSLINE
MED/94322283
AB Fourteen patients who received allogeneic bone marrow transplantation
(BMT) were examined 100 to 220 days after BMT. Ten out of 14 patients
were diagnosed as having chronic graft-versus-host disease (cGVHD) in
skin, liver, eyes and other organs. These cGVHD patients also had
objective evidence of oral involvement. Subjective xerostomia was
experienced by 7 cGVHD patients and decreased whole saliva flow was
observed in 4 cGVHD patients. However, no patient had a history of
parotid swelling or notable abnormality in parotid sialography. Labial
salivary glands (LSG) or 9 cGVHD patients showed atrophy and/or
destruction in association with diffusely infiltrating lymphocytes. The
infiltrating lymphocytes were mainly CD3+ T cells with a predominance of
CD8+ cells over CD4+ cells. Lichenoid lesions on the oral mucosa were
also observed in 5 cGVHD patients. Thus, thus study indicated that oral
examination, including LSG biopsy, is useful in the diagnosis of cGVHD.
DE Adolescence Adult Bone Marrow Transplantation/ADVERSE EFFECTS Chronic
Disease CD4-CD8 Ratio Female Graft vs Host
Disease/*DIAGNOSIS/ETIOLOGY Human Lichenoid Eruptions Male Middle
Age Mouth Diseases/*DIAGNOSIS/ETIOLOGY Mouth Mucosa/PATHOLOGY
Support, Non-U.S. Gov't Xerostomia/*DIAGNOSIS JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).